Piper Companies is seeking a Clinical Research Associate II (CRA II) to support a growing client in the biotechnology and oncology research industry in the United States. The Clinical Research Associate II (CRA II) role is fully remote with regional travel required to investigative sites as needed. The Clinical Research Associate II (CRA II) role is ideal for a clinical research professional with strong oncology monitoring experience and a proven track record of supporting Phase I-III clinical trials. Responsibilities of the Clinical Research Associate II (CRA II) include: Conduct routine site monitoring visits, including site initiation, interim monitoring, and closeout activities for oncology clinical trials. Evaluate site compliance with study protocols, ICH-GCP guidelines, and applicable regulatory requirements. Review source documentation and verify clinical data accuracy to ensure high-quality study execution. Partner with investigators, study coordinators, and cross-functional teams to proactively resolve site issues and drive enrollment goals. Prepare detailed monitoring reports and maintain study documentation throughout the clinical trial lifecycle. Requirements of the Clinical Research Associate II (CRA II) include: Bachelor's degree in Life Sciences, Nursing, or a related scientific field. 3+ years of independent monitoring experience as a Clinical Research Associate with a focus on oncology studies. Strong knowledge of ICH-GCP, FDA regulations, and clinical trial monitoring best practices. Experience supporting Phase I, II, and/or III oncology clinical trials, including site management responsibilities. Ability to travel up to 30-50% regionally as required. Compensation for the Clinical Research Associate II (CRA II) include: $105,000 - $125,000 annually Full Comprehensive Benefits: Health, Vision, Dental, PTO, Paid Holiday and Sick Leave if Required by Law. Fully remote work environment with travel reimbursement. This job opens for applications on 10/16/2026. Applications for this job will be accepted for at least 30 days from the posting date. Keywords: clinical research associate, CRA II, oncology, clinical trials, monitoring, GCP, FDA, biotech, pharmaceutical, remote, site monitoring, Phase I, Phase II, Phase III, oncology research