Note: The job is a remote job and is open to candidates in USA. Jade Biosciences is seeking a Senior Clinical Scientist to support clinical development programs in nephrology, particularly rare or immune-mediated kidney diseases. The role translates clinical strategy into execution of Phase 2 and Phase 3 trials, including study design, data review, regulatory support, and scientific communication.

Responsibilities

• Serve as the Clinical Scientist for one or more Phase 2 and/or Phase 3 clinical studies
• Contribute to study design, protocol development, and protocol amendments
• Develop and review study-related documents including:
• Protocols
• Investigator's Brochures
• Informed Consent Forms
• Clinical study reports
• Study manuals and training materials
• Safety management plans
• Provide scientific oversight throughout study conduct to ensure protocol compliance and data quality
• Partner closely with Clinical Operations to support study start-up, enrollment, trial execution, and close-out activities
• Participate in investigator meetings, site training, and scientific discussions with investigators and key opinion leaders
• Lead ongoing data review and medical monitoring activities in collaboration with Medical Monitors
• Identify clinical trends, protocol deviations, safety signals, and data quality issues
• Collaborate with Data Management and Biostatistics to develop:
• Data review plans
• Edit check specifications
• Endpoint derivation and analysis plans
• Participate in database lock, data cleaning, and analysis activities
• Contribute to interpretation of study results and development of key messages
• Support preparation of regulatory submissions and agency interactions
• Assist in development of briefing documents and responses to regulatory questions
• Ensure study conduct aligns with ICH-GCP, applicable regulations, and company standards
• Work effectively across Clinical Development, Clinical Operations, Biometrics, Regulatory, Safety, Medical Affairs, and Medical Writing
• Drive timelines, track deliverables, and proactively identify and mitigate risks
• Support governance meetings and preparation of study review materials
• Contribute to abstracts, presentations, manuscripts, and scientific publications
• Participate in advisory boards, investigator meetings, and key external scientific interactions
• Maintain awareness of evolving scientific, clinical, and competitive landscapes

Skills

• Advanced degree in life sciences, nursing, pharmacy, public health, or related discipline (PharmD, PhD, MS, MPH, or equivalent)
• Minimum 5–8 years of clinical research experience in the biotechnology, pharmaceutical, or CRO industry
• Experience supporting Phase 2 and/or Phase 3 clinical trials
• Strong understanding of clinical trial design, clinical data review, and drug development
• Working knowledge of ICH-GCP, FDA, EMA, and global regulatory requirements
• Experience reviewing clinical data and collaborating with biostatistics and data management teams
• Excellent project management, communication, and organizational skills
• Ability to work independently and manage multiple priorities in a fast-paced environment
• Strong scientific and analytical thinking
• Attention to detail with a focus on data quality
• Excellent written and verbal communication skills
• Collaborative and team-oriented mindset
• Ability to influence across functions without direct authority
• Comfortably operating in a highly dynamic, entrepreneurial environment
• Proactive, hands-on, and solution-oriented approach
• Experience in nephrology, immunology, inflammation, autoimmune diseases, or rare diseases
• Experience with global multicenter clinical trials
• Prior involvement in regulatory submissions and health authority interactions
• Experience contributing to scientific publications and conference presentations
• Experience working in a small or emerging biotechnology company

Benefits

• The role is fully remote.

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