Note: The job is a remote job and is open to candidates in USA. TetraScience is the Scientific Data and AI Company building Tetra OS, an operating system for scientific intelligence that helps life sciences firms transform scientific data into AI-native assets and workflows. The Senior .NET Engineer will design and develop scalable distributed applications, build full-stack services and user interfaces, implement microservices and automated testing, maintain CI/CD pipelines, and support production debugging and observability using AWS and related technologies.

Responsibilities

• Architect, design, and maintain distributed applications, ensuring high performance, scalability, and security
• Develop backend services (primarily C#/.NET and TypeScript) and cloud APIs, as well as modern, responsive front-end applications using TypeScript/React
• Design and implement loosely coupled, independently deployable services using AWS services such as DynamoDB, RDS, SQS, Lambda, API Gateway, and others
• Create and maintain automated unit, integration, contract, and end-to-end tests across microservices and UI layers
• Use GitHub Actions to implement and maintain CI/CD pipelines for both backend services and front-end applications
• Diagnose and resolve production issues in distributed systems, including service-to-service communication, CPU/memory/network bottlenecks, and AWS service performance
• Instrument services using OpenTelemetry (or equivalent) to enable earlier fault detection, clearer alerting, and stronger operational visibility. Contribute to SLO definition and MTTR reduction efforts across the platform
• Work closely with product managers, tech leads, and other engineers to deliver reliable, maintainable, and scalable solutions. Communicate technical decisions clearly to both technical and non-technical stakeholders

Skills

• Proven track record in designing and building distributed applications
• Strong proficiency in backend service development using C#/.NET
• Strong proficiency in TypeScript and React for front-end UI
• Experience building and operating software in both on-premises/customer-hosted environments and cloud-native multi-tenant environments, with an understanding of how debugging, deployment, and scaling differ between the two
• Hands-on experience with AWS DynamoDB, RDS, SQS (or an equivalent cloud provider) in production environments
• Experience with microservices patterns (service discovery, API gateway, messaging/queueing, data partitioning)
• Experience with automated testing at multiple levels
• Strong Git skills and hands-on experience with GitHub Actions for CI/CD
• Strong troubleshooting skills for distributed systems in production
• Solid understanding of cloud-native architecture and AWS best practices
• Familiarity with observability tooling and practices (OpenTelemetry, structured logging, distributed tracing, metrics-based alerting) to support proactive issue detection
• Excellent verbal and written communication
• Strong collaboration skills in cross-functional teams
• Analytical mindset with high attention to detail
• No visa sponsorship is available for this position
• Familiarity with containerization (Docker) and experience defining AWS infrastructure using CloudFormation (or AWS CDK) to support predictable and repeatable environments
• Experience with performance tuning and designing scalable solutions
• Experience with, or exposure to, scientific instrument software / Chromatography Data Systems (CDS) e.g., Waters Empower, Thermo Chromeleon, Cytiva UNICORN, Agilent OpenLab, along with knowledge of instrument integration pattern and practices is a strong plus

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