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[Remote] Senior Staff Software Engineer

Remote · Vietnam Full-time

Note: The job is a remote job and is open to candidates in USA. Freenome is hiring a Senior Staff Software Engineer for its Platform team. The role shapes the platform’s technical direction, builds and operates scalable cloud services, supports research and domain teams, and advances AI adoption and secure AI-powered workflows.

Responsibilities

  • Shape Platform’s technical vision and roadmap, working with engineering and R&D leaders to align platform priorities with company goals
  • Treat Platform and Data as Products, building trust with leads and SMEs from domain teams, and translating shared needs into reusable platform solutions
  • Design and ship scalable platform systems, evolving the architecture through reviews, rapid prototypes, and pragmatic technology choices
  • Drive business-critical initiatives, resolving tradeoffs, sequencing work into incremental deliverables and delegating to scale execution
  • Support platform users to unblock critical work, troubleshoot complex system issues, and turn recurring issues into lasting reliability and capacity improvements
  • Champion AI adoption across Freenome, pairing with domain experts and tailoring guidance and tools to varied technical backgrounds
  • Expand our team’s impact by using AI for platform enhancements, and by building platforms for AI that empower Freenome users to create and deploy secure, cost-effective agentic workflows and LLM-powered applications
  • Increase visibility of cloud costs, recommend and drive initiatives to reduce waste while protecting performance, reliability, and scientific productivity
  • Grow other engineers through pairing, design review, delegation and feedback, while modeling Freenome’s values and reinforcing a high-performing culture

Skills

  • 12+ years of relevant software engineering experience or equivalent, preferably in platform teams, delivering complex systems from design to production
  • 3+ years guiding complex initiatives end-to-end across teams: aligning stakeholders, communicating tradeoffs clearly, and enabling delivery without formal authority
  • 3+ years building and operating production platforms using Infrastructure as Code on a public cloud, preferably Azure or GCP
  • Proficiency in Python and at least one other high-level programming language
  • Deep knowledge of Linux internals, networking and virtualization, with hands-on troubleshooting and performance tuning at system level
  • Solid Kubernetes expertise, with experience owning one or more advanced capabilities such as controllers, operators and CRDs, admission control, scheduling, autoscaling, service mesh, or multi-cluster networking
  • Sound judgment in distributed systems and platform design, including governance, capacity, reliability, cost, data processing and storage
  • Software architecture leadership: you ship clean code, write clear design docs and ADRs, and guide constructive reviews and collaborative technical decisions
  • You are a force multiplier who enjoys helping engineers or domain experts grow, with a track record of making teams more capable and independent
  • Success partnering with one or more specialist teams - such as data science, AI/ML, computational biology or related fields - to improve their workflows
  • Hands-on AI-assisted development and a record of building reusable tools or workflow automation
  • Life-sciences software, NGS pipelines and biological data
  • ML Ops, model development and deep learning
  • Scientific Python frameworks and data-science technology stack
  • Workflow orchestration and distributed compute frameworks on Kubernetes
  • Cloud migrations, multi-cloud or multi-region operations
  • Columnar processing, open lakehouse technologies, and modern table formats such as Apache Iceberg
  • FinOps practices, workload cost attribution, and measurable cloud savings

Benefits

  • Equity
  • Cash bonuses
  • A full range of medical, financial, and other benefits

Company Overview

  • Freenome is a biotechnology company developing blood tests for early cancer detection to improve access to routine screening. It was founded in 2014, and is headquartered in Brisbane, California, USA, with a workforce of 201-500 employees. Its website is https://www.freenome.com.
  • Company H1B Sponsorship

  • Freenome has a track record of offering H1B sponsorships, with 6 in 2026, 7 in 2025, 11 in 2024, 15 in 2023, 10 in 2022, 7 in 2021, 7 in 2020. Please note that this does not guarantee sponsorship for this specific role.
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