Piper Companies is seeking a Senior Clinical Project Manager to support a growing organization in the biotechnology and clinical research industry. The Senior Clinical Project Manager role is fully remote. The Senior Clinical Project Manager role is ideal for an experienced clinical operations leader with expertise managing global clinical trials across Cardiovascular, MASH, Hepatology, Obesity, and Dermatology therapeutic areas. Responsibilities of the Senior Clinical Project Manager include: Direct the planning, execution, and oversight of Phase I-IV clinical trials, ensuring studies are delivered on schedule, within budget, and in compliance with regulatory requirements. Serve as the primary liaison between sponsors, CROs, clinical sites, vendors, and cross-functional stakeholders to drive study objectives and milestones. Monitor trial progress, identify operational risks, and implement mitigation strategies to maintain study quality and performance. Oversee study timelines, enrollment metrics, vendor activities, and financial tracking to support successful clinical program execution. Lead cross-functional study teams and provide strategic guidance throughout protocol implementation, database lock, and study closeout activities. Requirements of the Senior Clinical Project Manager include: 8+ years of clinical project management experience within biotechnology, pharmaceutical, or CRO environments. Proven experience managing clinical trials within Cardiovascular, MASH, Hepatology, Obesity, and/or Dermatology therapeutic areas. Strong knowledge of ICH-GCP guidelines, FDA regulations, and global clinical trial operations. Experience managing CROs, vendors, budgets, timelines, and multinational clinical studies. Bachelor's degree required; advanced degree in Life Sciences, Public Health, Nursing, or a related discipline preferred. Compensation for the Senior Clinical Project Manager include: $170,000-200,000 annually plus bonus Full Comprehensive Benefits: Health, Vision, Dental, PTO, Paid Holiday and Sick Leave if Required by Law. Fully remote work environment. This job opens for applications on 10/16/2026. Applications for this job will be accepted for at least 30 days from the posting date. Keywords: senior clinical project manager, clinical project manager, clinical operations, cardiovascular, MASH, metabolic dysfunction-associated steatohepatitis, hepatology, liver disease, obesity, dermatology, clinical trials, CRO management, ICH-GCP, remote, biotechnology, pharmaceutical